Oh, come on, the altittude isn't all that bad. But then, I also live in Denver, so I'm well used to the thin air.
In reference to the original question, yes, you can expect to go slower then normal, sea level races. It takes about six weeks to full aclimatize to the higher altitude, so coming up a week or two early really doesn't help. You're heart rate will be much higher becasue of the increased effort to get the O2 to the working muscles. I wouldn't recommed running MHCM for time if you are from sea level.
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