First of all, good luck! For your information, the US women's olympic marathoner did much of her training on a treadmill (she lives in Alaska).
However, I echo what was said earlier. Sometimes, for my long runs, I'll do a mix; say 15 miles (25 km) outside, then another 5 miles (8 km) on the treadmill. I believe that it is better to get used to the surface that you will be running on. I don't make it a point to wear exactly the same clothing as I will on race day, but I do like to get in a few long runs with my "marathon shoes".
As far as being lethargic, here is what I do: 1) I drink lots and lots of water and 2) I go out slowly for 20 minutes or so. If I still feel terrible, then I go home; but the vast majority of the time I feel ok by then. The time I don't even try is if I have a fever!!!
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