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I have only done the one marathon(yesterday in LA) and may not be the best qualified to give advice, but - I would stick to the 12:00 pace for the first 10 miles or so and see how you feel and increase your speed in small increments up to about mile 19. If you feel strong at mile 19, increase a little more until about mile 23 and then finish the last two miles increasingly faster. The thing is that a lot can change from mile 19 to the finish. You can feel good at mile 19 and feel completely different at 21 and so on. So I would really be in touch with how you physically feel so that you can increase your effort accordingly. Also I noticed that at about mile 21 it gets mental. You are that close to the finish, yet a mental will to get to the finish comes into play. That's okay, though. Taking on the mental part is what makes you feel so accomplished at the finish.
You sound like your ready - listen to your body, fuel it with gatorade and water (the gatorade was key for me) and go have a good race!
*Note, I only looked at the splits at the mile marks along the race. I did not wear a watch. I truly ran according to how I felt. I had an idea of what my splits needed to be to finish under 4:00, but I was not running for that. I think that I ran better by not focusing on a watch. That's just me, though. Yet it is something to think about.
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