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Your distress could be caused by something you put in your stomach (too much salt or sugar) or something you didn't (dehydration).
Check the following site for a lengthy Q&A forum on stomach problems; you may find a situation analogous to yours there: www.fred.net/ultrunr/stomach.html
As for prevention, read Richard's suggestions here for proper hydration. Go to the RunningTips/Training board, then scroll to the 4/2/01 thread called "Does the Last 6.2 Ever Feel Better???" Richard posted on 4/13/01 the reply "Yes, if you run the first part slower than the second half."
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